Malaysia has seen a rise in electronic cigarette (EC) use, raising concerns about health effects. Limited local data on EC vapors hampers comprehensive risk assessments. This study estimated health risks linked to selected aldehydes and heavy metals in EC vapors from locally-made e-liquids. The chemical analyses showed concerning average concentrations of formaldehyde, acetaldehyde, aluminum, chromium, iron, nickel, copper, cadmium, and lead operated under low and high wattage settings. Health risk assessment suggested carcinogenic risks for 1-2 out of 10,000 EC users.