In Australia, nicotine vaping product (NVP) use has become a significant public health risk due to the associated health issues and rise in popularity, particularly among children and young adults. We will explore Queensland’s first investigations and prosecutions for unauthorised dealings with NVPs under the Medicines and Poisons Act 2019. We delve into the legal intricacies and critical components of notable cases, including regulatory frameworks, legal precedents, and enforcement strategies and barriers. We provide valuable insight into the evolving landscape of NVP regulation in Australia and how that fits into a global context.